This is an Edo period pamphlet that we still publish.

Meiji period chemical analysis of Kita onsen's waters,
published by the Tochigi Prefectural authorities.
Chemical analysis of Ainoyu published in Meiji 20, (1887).
Chemical analysis of Tengonoyu published in Meiji 20, (1887)
also giving recommendations for their use.
This Noren (shop curtain) hanging behind the front desk is from the Meiji period.